Soft Matter theory group focuses on the development new theoretical methods and application of molecular modelling techniques to problems of interest for the scientific and technological community. In particular, the group offers a transversal and multidisciplinary approach, combining aspects of Physics, Mathematics and Computer Science in Biophysics and Soft Matter field.
Here are three main research lines:
It is generally accepted that smaller the size of the object, easier to cross the barriers. Here we see opposite scenario: NPs with size > 5 nm can cross the bilayer spontaneously (DOI: 10.1126/sciadv.1600261).
The veined wing of the clanger cicada kills bacteria solely through its physical structure — one of the first natural surfaces found to do so. An international team of biophysicists has now come up with a detailed model of how this defence works on the nanoscale. (DOI: 10.1038/nature.2013.12533)
First reported physical bactericidal activity of black silicon or indeed for any hydrophilic surface. Black silicon represents an excellent prospect for the development of a new generation of mechano-responsive, antibacterial nanomaterials (DOI: 10.1038/ncomms3838).
We find that the energy cost of the bilayer rupture is quite high compared to that of the energy of thermal motion. This conclusion may indirectly support other energy-dependent translocation mechanisms, such as, for example, endocytosis (DOI: 10.1021/nn1016549).
Multidisciplinary EU-funded 7th Framework Programme specially designed to provide scientific and transferable skill training and career development for early stage researchers and experienced researchers in the field of lipid research.
Suggested mechanism of a lipid-covered hydrophobic nanoparticle spontaneously crossing lipid bilayer. This mechanism is directly observed in specially designed microfluidic device.
Dragonfly expedition to Massif Els Ports in collaboration with Museu de les Terres de l'Ebre, Amposta, Swinburne University of Technology, Australia and Universitat Rovira i Virgili, Tarragona.